Articles

  1. Maxfibe Sachets: The Invisible Natural Fiber Download Article

    GovindShukla, Anusha Palkamshetti, K.Srinidhi, C.J. Sampath Kumar
    • Article Type: Research Article
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    • Pages (101-107)
    • No of Download = 32

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    A prebioticis defined as “a nondigestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon” Modification by prebiotics of the composition of the colonic microflora leads to the predominance of a few of the potentially health-promoting bacteria.  The scientific data showing that prebiotics may positively affect various physiologic functions in ways that will permit them now or in the future to be classified as functional foods for which health claims (of enhanced function or of reduction in disease risk) will be authorized. The present paper Reviews the Role of  Maxfibe Sachets developed by R&D cell of Lactonova Nutripharm Pvt Ltd. Hyderabad.

  2. Enancement of solubility of dronedarone by using solid dispersion technique Download Article

    N.Sandeepthi , Nellutla Jhancy Laxmi, N.Sriram, Kuldeep p waidya
    • Article Type: Research Article
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    • Pages (108-115)
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    Definition of solid dispersions: Chiou and Riegelman defined the term solid dispersion as    a “dispersion of one or more active ingredients in an inert carrier or matrix at a solid state prepared by the melting (fusion), solvent or melting solvent method.

    Cardiac arrhythmias: A cardiac arrhythmia is a disturbance or irregularity in the heart rate,   rhythm, or both. An arrhythmia may occur as a result of heart disease or from a disorder that affects cardiovascular function. Conditions such as emotional stress, hypoxia, and electrolyte imbalance also may trigger an arrhythmia.

  3. Development of new analytical method for the determination of Aceclofenac by hydrotropic solubilisation technique and its validation Download Article

    Dr.K.RajeswarDutt, D.Madhu, Heena, K.Sankeerthana, M.Laharika, Md.AktharSulthana, N.Sravan, R.Maheshwari, I.Santhosh, Dr.K.N.V. Rao & Dr.B.Reddy
    • Article Type: Research Article
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    • Pages (116-122)
    • No of Download = 28

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    A thorough literature survey of the various analytical methods for the quantitative estimation of Aceclofenac in both  bulk  drug  and  dosage  forms  has  revealed  that  very  few  analytical  methods  are  available  utilizing  the hydrotropic  solubiliation  technique to date. The present research paper is a description of a new analytical method developed  using  the principle  of Hydrotropy employing  very easily available  chemicals  namely 1M Sodium  bicarbonate and 1M urea solutions.  The  method  has  been  validated  as  per  ICH  guidelines  and  found  to  conform  to  ICH guidelines.  In  the  present  investigation  the  use  of  organic  solvent  has  been  avoided  due to their  high  cost, volatility and  toxicity, making  the method  environmental  friendly. The findings revealed that the method is new, simple, safe, environmental friendly, accurate, precise, reproducible   and   cost-effective. It can be successfully  employed as  a  routine  analytical  procedure  for  the  analysis  of  Aceclofenac tablets. Hence the authors  suggest  that  this analytical  method  can  be  adopted  in  the  Pharmaceutical  industry for the  analysis  of Aceclofenac in bulk and various dosage forms. Aceclofenac shows its maximum absorbance at 226 nm and Beer’s law was obeyed in concentration range of 1-5µg/ml   in   presence of 1M Sodium bicarbonate and 1M Urea and   Molar absorptivity was found to be8.382 mol-1 cm-1 ×103. The statistical analytical parameters namely Correlation coefficientand Regression equation were computed and found to be 0.993 and 0.052x+0.57.

  4. Cystocran Tablet; A natural safeguard in urinary tract infections Download Article

    GovindShukla, AnushaPalkamshetti, C.J. Sampath Kumar
    • Article Type: Research Article
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    • Pages (123-130)
    • No of Download = 13

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    Urinary tract infections (UTIs) are a serious health problem affecting millions of people each year. Infections of the urinary tract are the second most common type of infection in the body. One woman in five develops a UTI during her lifetime. Natural remedies have been used for centuries to alleviate pain and discomfort as well as address the underlying symptoms. Natural remedies for urinary tract infections are safe and cause no side effects. They also support one’s physical, mental, and emotional health, rather than simply treating UTI symptoms. A number of antibiotics can be prescribed to treat urinary tract infections. However, certain antibiotics may not be safe for these pregnant, plan to become pregnant or are breast feeding women. Like all medications, antibiotics have side effects. These medications can produce reactions and even serious medical complications in some women. In addition, adverse reactions to antibiotics may be more serious in women with weakened immune systems, including women with diabetes. Possible side effects of antibiotics include allergic reactions, fever, nausea and bloating. Vaginal yeast infections are another common side effect of antibiotic use in women. Antibiotics kill bacteria, including bacteria that control the amount of other normal body organisms, such as yeast. So the reduction in bacteria can result in an overgrowth of yeast. Taking certain antibiotics during pregnancy may be a risky proposition since women who take them may deliver babies with increased risk of birth defects. The present Article reviews the role of cystocran in Preventing Urinary tract infections.

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