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  1. Analytical method development and validation for the estimation of quinapril and tolcapone using RP-HPLC Download Article

    Mr. Suresh Babu, T.Adinarayana, S.Santhosh, S.Sankar, SK.Rehana
    • Article Type: Research Article
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    • Pages (207-229)
    • No of Download = 28

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    A simple and selective LC method is described for the determination of Quinapril and Tolcapone tablet dosage forms. Chromatographic separation was achieved on a c18 column using mobile phase consisting of a Mixed Phosphate buffer (KH2PO4 +K2HPO4): Acetonitrile 40:60, with detection of 239 nm. Linearity was observed in the range 50 - 150 µg /ml for Quinapril (r2 =0.995) and 62.5- 187.5µg /ml for Tolcapone (r2 =0.999) for the amount of drugs estimated by the proposed methods was in good agreement with the label claim.

    The proposed methods were validated. The accuracy of the methods was assessed by recovery studies at three different levels. Recovery experiments indicated the absence of interference from commonly encountered pharmaceutical additives. The method was found to be precise as indicated by the repeatability analysis, showing %RSD less than 2. All statistical data proves validity of the methods and can be used for routine analysis of pharmaceutical dosage form.

  2. Nutrease powder; a natural plant based nutritional shake with co-factors & co-nutrients for better absorption & efficacy Download Article

    Govind Shukla, Nagalakshmi Yaparthy, NehaGiri, D.Sruthi Rao, G.Santosh, C.J. Sampath Kumar
    • Article Type: Research Article
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    • Pages (230-239)
    • No of Download = 30

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    Nutrease powder is an effective natural vitamin and minerals Nutritional supplementation to improve  metabolism. Nutrease powder just ½ serving (1 scoop)   Provides 150 calories,18 grams of protein, 12 grams of  fiber, and 1 gram of sugar per day.  Nutrease powder Supports effective weight management, Reduces hunger and cravings, Promotes energy and positive mood, Promotes loss of fat and preservation of lean body mass, Improves metabolism and insulin sensitivity. This article reviews the current available scientific literature regarding the effect of nutrease powder as an effective supplementation for daily energy needs.

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